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What to Expect Immediately After Taking Suboxone

Mar 10, 2025
What to Expect Immediately After Taking Suboxone
Opiate use disorder is a medical condition, not a weakness or failing. If you’re ready to take the first step toward a brighter future, Suboxone® can help you manage cravings and withdrawal symptoms, so you can focus on your recovery.

The decision to reclaim your life from opioid use disorder (OUD) takes tremendous courage. Some 2.1 million Americans struggle with OUD, but breaking free from addiction is possible; support is within reach.

At Free Range Mental Health, board-certified psychiatric nurse practitioner Dan Watts, DNP, APRN, PMHNP-BC, can help you manage your recovery safely and effectively with medication-assisted treatment (MAT), like Suboxone®.

If you’re starting Suboxone treatment, you’re taking a big step toward a brighter future. Here, we guide you through what to expect immediately after taking Suboxone, offering practical advice as you begin this new chapter.

Your Suboxone experience

Suboxone combines buprenorphine and naloxone to help control cravings and ease withdrawal symptoms associated with OUD. It’s typically available as a dissolvable film or tablet.

Before starting treatment, you meet with Dan for a consultation to discuss your needs and goals. He can determine if Suboxone is the right fit for your recovery plan and explain the preparation process, which includes abstaining from opioids for 12-24 hours prior to treatment.

While everyone’s experience is unique, here’s what you may encounter after taking your first dose:

The initial effects

Once it dissolves under your tongue, Suboxone starts working relatively quickly. While some patients feel immediate relief, others may find the initial effects more subtle.

As the medication stabilizes your system, unpleasant withdrawal symptoms — such as muscle pain, sweating, restlessness, and anxiety — should gradually fade, allowing you to feel more comfortable and focused. 

If you’re still experiencing cravings or significant withdrawal symptoms after the first day, or if you’re feeling overly sedated or groggy, let Dan know. He can make small adjustments until we find the dosage that works best.

Navigating potential side effects

Suboxone is generally safe and effective, but like any medication, it can sometimes cause side effects — particularly at first, as your body adjusts. 

Common side effects include nausea, constipation, headache, and difficulty sleeping. However, these are typically temporary and manageable. For example, eating a meal about 30 minutes before taking Suboxone may help with nausea, and increasing your fluid and fiber intake can lessen constipation.

If you’re dealing with persistent or bothersome side effects, don’t hesitate to reach out to Dan. We can work together to find solutions, whether it’s adjusting your dose, recommending over-the-counter (OTC) remedies, or exploring other options.

Your next steps

Over time, cravings and withdrawal symptoms should become less frequent and less intense, freeing you to focus more on your recovery. You may find it easier to participate in therapy, work on personal goals, and strengthen your relationships.

While some days may be better than others, the overall trend should be toward feeling more grounded and in control. There may be challenges along your path to sobriety, but with continued treatment and support, you can build a strong foundation for lasting wellness.

OUD is a medical condition, not a weakness or failing. It requires understanding, support, and effective treatment. Are you ready to take the first step? Schedule an appointment at Free Range Mental Health in Northfield, Minnesota, online or by phone today.